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Rabbit Polyclonal Antibody to PTPN22
货号: P01680
别名: LYP; PEP; LYP1; LYP2; PTPN8
应用: IHC
反应种属: Human, Mouse
抗体类型: Primary antibody
Swissprot: Q9Y2R2
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Description

This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Specification

Aliases LYP; PEP; LYP1; LYP2; PTPN8
Swissprot Q9Y2R2
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Fusion protein of human PTPN22
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

IHC 1/30-1/150
ELISA 1/2000-1/5000
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