Rabbit Polyclonal Antibody to SKIL
货号：
P01824
别名：
SNO; SnoA; SnoI; SnoN
应用：
WB,IHC
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
P12757
规格：
目录价
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Description |
|---|
The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. |
Specification |
|
|---|---|
| Aliases | SNO; SnoA; SnoI; SnoN |
| Swissprot | P12757 |
| WB Predicted band size | 77 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human SKIL |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/200-1/1000 |
| IHC | 1/30-1/150 |
| ELISA | 1/1000-1/2000 |
Product Image
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Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Huvec cells, Primary antibody: P01824(SKIL Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
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The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P01824(SKIL Antibody) at dilution 1/30. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P01824(SKIL Antibody) at dilution 1/30. (Original magnification: ×200)
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