Mouse Monoclonal Antibody to Cytokeratin 18
货号：
20276
别名：
CK18; CYK18; KRT18
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P05783
规格：
目录价
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Description |
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Cytokeratin 18, also known as CK18, CYK18, KRT18. Entrez Protein NP_000215. It encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. |
References |
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| 1. Cancer Genet Cytogenet. 2007 Oct 15;178(2):94-103. 2. J Mol Histol. 2008 Apr;39(2):209-16. |
Specification |
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|---|---|
| Aliases | CK18; CYK18; KRT18 |
| Entrez GeneID | 3875 |
| Swissprot | P05783 |
| clone | 4D11E4 |
| WB Predicted band size | 48kDa |
| Host/Isotype | Mouse IgG2b |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human Cytokeratin 18 (aa391-483) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| IHC | 1/200 - 1/1000 |
| ELISA | 1/10000 |
Product Image
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Western blot analysis using CK18 mouse mAb against Hela (1), NIH/3T3 (2), A549 (3), Jurkat (4), MCF-7(5), HepG2 (6), A431 (7), HEK293 (8) and K562 (9) cell lysate.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma (A), hepatocarcinoma (B), stomach cancer (C) and colon cancer tissue (D), showing cytoplasmic location with DAB staining using CK18 mouse mAb.
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