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Mouse Monoclonal Antibody to MYL2
货号: 20324
别名: MLC2; CMH10; DKFZp779C0562
应用: WB
反应种属: Human
抗体类型: Primary antibody
Swissprot: P10916
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Description

MYL2(myosin, light chain 2, regulatory, cardiac, slow), also known as MLC-2, MLC2v. Entrez protein NP_000423. MYL2 associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. It is an hexamer of two heavy chains and four light chains that is predominantly expressed in adult cardiac ventricle muscle. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.

References

1. DNA Seq. 2003 Oct;14(5):339-50.
2. Oncogene. 2002 Aug 29;21(38):5852-60.

Specification

Aliases MLC2; CMH10; DKFZp779C0562
Entrez GeneID 4633
Swissprot P10916
clone 7C9
WB Predicted band size 19kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of MYL2 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.

Application

WB 1/500 - 1/2000
ELISA 1/10000
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