Mouse Monoclonal Antibody to LPA
货号：
20294
别名：
LP; AK38; APOA; LPA
应用：
IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P08519
规格：
目录价
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Description |
|---|
LPA: lipoprotein, Lp(a). Apo(a) is the main constituent of lipoprotein(a) (lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1.Lp(a) may be a ligand for megalin/gp 330.Apo(a) is known to be proteolytically cleaved, leading to the formation of the so-called mini-lp(a).Apo(a) fragments accumulate in atherosclerotic lesions,where they may promote thrombogenesis.O-glycosylation may limit the extent of proteolytic fragmentation. |
References |
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| 1. J Stroke Cerebrovasc Dis. 2007 Sep-Oct;16(5):220-4. 2. Clin Chim Acta. 2008 Jan;387(1-2):109-12. |
Specification |
|
|---|---|
| Aliases | LP; AK38; APOA; LPA |
| Entrez GeneID | 4018 |
| Swissprot | P08519 |
| clone | 8F6A9 |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of LPA (1823－2013) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| IHC | 1/200 - 1/1000 |
| ELISA | 1/10000 |
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