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Mouse Monoclonal Antibody to LIN28
货号: 20271
别名: CSDD1; LIN-28; LIN28A; ZCCHC1
应用: WB,IF
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q9H9Z2
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Description

LIN28: lin-28 homolog (C. elegans), also known as CSDD1, ZCCHC1. Entrez Protein NP_078950. LIN28 was first discovered in the nematode C. elegans. It is a heterochronic protein in C. elegans involved in the timing of developmental events and choice of stage specific cell fates. LIN28 expression has been found to be regulated post-transcriptionally by miRNAs in both nematodes and mammals. In humans it is expressed in embryonic stem cells and its expression decreases during differentiation. It is negatively regulated by retinoic acid in neuronal differentiation.

References

1. Dev Dyn. 2005 Feb;232(2):487-97.
2. Mol Cell Biol. 2005 Nov;25(21):9198-208.

Specification

Aliases CSDD1; LIN-28; LIN28A; ZCCHC1
Entrez GeneID 79727
Swissprot Q9H9Z2
clone 6D1F9
WB Predicted band size 23kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of LIN28 (aa93-209) expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.

Application

IF 1/200 - 1/1000
ELISA 1/10000
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