Rabbit Polyclonal Antibody to QDPR
货号:
P02867
别名:
DHPR; PKU2; HDHPR; SDR33C1
应用:
WB,IHC
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
P09417
规格:
目录价
在线咨询
Description |
---|
This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase. |
Specification |
|
---|---|
Aliases | DHPR; PKU2; HDHPR; SDR33C1 |
Swissprot | P09417 |
WB Predicted band size | 26 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Fusion protein of human QDPR |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
---|---|
WB | 1/500-1/2000 |
IHC | 1/50-1/200 |
ELISA | 1/5000-1/10000 |
Product Image
-
Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-5: Mouse liver tissue, Mouse brain tissue, Rat brain tissue, Rat liver tissue and Human fetal liver tissue lysates, Primary antibody: P02867(QDPR Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 30 seconds
-
The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P02867(QDPR Antibody) at dilution 1/70. (Original magnification: ×200)
-
The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P02867(QDPR Antibody) at dilution 1/70. (Original magnification: ×200)