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Mouse Monoclonal Antibody to DKK1
货号: 20325
别名: SK; DKK-1;
应用: FCM
反应种属: Human,Mouse
抗体类型: Primary antibody
Swissprot: O94907
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Description

DKK1: dickkopf homolog 1 (Xenopus laevis), also known as SK. Entrez Protein NP_036374. DKK1 is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.

References

1. Dev Cell. 2008 Jul;15(1):37-48.
2. Cancer Lett. 2008 Sep 28;269(1):67-77.

Specification

Aliases SK; DKK-1;
Entrez GeneID 22943
Swissprot O94907
clone 2H2
WB Predicted band size 28.7kDa
Host/Isotype Mouse IgG2b
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Purified recombinant fragment of DKK1 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.

Application

FCM 1/200 - 1/400
ELISA 1/10000
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