Rabbit Polyclonal Antibody to ITM2C
货号：
P03317
别名：
E25; BRI3; E25C; ITM3; BRICD2C
应用：
WB
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
Q9NQX7
规格：
目录价
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Description |
|---|
Negative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation. |
Specification |
|
|---|---|
| Aliases | E25; BRI3; E25C; ITM3; BRICD2C |
| Swissprot | Q9NQX7 |
| WB Predicted band size | 30 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human ITM2C |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/2000 |
| ELISA | 1/5000-1/10000 |
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