Rabbit Polyclonal Antibody to CRACR2A
货号：
P03428
别名：
EFCAB4B
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q9BSW2
规格：
目录价
在线咨询
Description |
|---|
Ca2+-binding protein that plays a key role in store-operated Ca2+ entry (SOCE) in T-cells by regulating CRAC channel activation. Acts as a cytoplasmic calcium-sensor that facilitates the clustering of ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+concentration. It thereby regulates CRAC channel activation, including translocation and clustering of ORAI1 and STIM1. Upon increase of cytoplasmic Ca2+resulting from opening of CRAC channels, dissociates from ORAI1 and STIM1, thereby destabilizing the ORAI1-STIM1 complex. |
Specification |
|
|---|---|
| Aliases | EFCAB4B |
| Swissprot | Q9BSW2 |
| WB Predicted band size | 46 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Fusion protein of human CRACR2A |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/2000 |
| IHC | 1/150-1/300 |
| ELISA | 1/5000-1/10000 |
Product Image
-
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: 293T cell lysate, Primary antibody: P03428(CRACR2A Antibody) at dilution 1/900, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 1 minute
-
The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P03428(CRACR2A Antibody) at dilution 1/105. (Original magnification: ×200)
鄂公网安备42018502007531号
