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Mouse Monoclonal Antibody to AXL
货号: 20332
别名: UFO; JTK11
应用: WB,IF
反应种属: Human
抗体类型: Primary antibody
Swissprot: P30530
规格:
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Description

AXL: AXL receptor tyrosine kinase, also known as UFO, JTK11. Entrez Protein NP_001690. It is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.

References

1. Br J Cancer. 2006 May 22;94(10):1446-51.
2. Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5799-804.

Specification

Aliases UFO; JTK11
Entrez GeneID 558
Swissprot P30530
clone 7E10
WB Predicted band size 97.4kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant extracellular fragment of human AXL fused with hIgGFc tag expressed in HEK293 cell line.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

IF 1/200 - 1/1000
ELISA 1/10000
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