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Rabbit Polyclonal Antibody to PDZK1
货号: P03593
别名: CAP70; CLAMP; PDZD1; NHERF3; NHERF-3
应用: IHC
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q5T2W1
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Description

This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Specification

Aliases CAP70; CLAMP; PDZD1; NHERF3; NHERF-3
Swissprot Q5T2W1
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Fusion protein of human PDZK1
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

IHC 1/50-1/200
ELISA 1/5000-1/10000
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