Rabbit Polyclonal Antibody to CST3
货号:
P03755
别名:
ARMD11
应用:
WB,IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P01034
规格:
目录价
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Description |
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The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. |
Specification |
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Aliases | ARMD11 |
Swissprot | P01034 |
WB Predicted band size | 16 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthetic peptide of human CST3 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/1000-1/5000 |
IHC | 1/50-1/200 |
ELISA | 1/2000-1/10000 |
Product Image
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Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal brain tissue, Primary antibody: P03755(CST3 Antibody) at dilution 1/2400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
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The image is immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using P03755(CST3 Antibody) at dilution 1/50. (Original magnification: ×200)