Rabbit Polyclonal Antibody to ADRA1B
货号:
P03771
别名:
ADRA1, ALPHA1BAR
应用:
WB,IHC
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
P35368
规格:
目录价
在线咨询
Description |
---|
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. |
Specification |
|
---|---|
Aliases | ADRA1, ALPHA1BAR |
Swissprot | P35368 |
WB Predicted band size | 57 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Synthetic peptide of human ADRA1B |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
---|---|
WB | 1/200-1/1000 |
IHC | 1/25-1/100 |
ELISA | 1/1000-1/5000 |
Product Image
-
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human lung cancer tissue, Primary antibody: P03771(ADRA1B Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
-
The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P03771(ADRA1B Antibody) at dilution 1/20. (Original magnification: ×200)
-
The image is immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using P03771(ADRA1B Antibody) at dilution 1/20. (Original magnification: ×200)