Rabbit Polyclonal Antibody to CCR8
货号:
P03804
别名:
CY6, TER1, CCR-8, CKRL1, CDw198, CMKBR8, GPRCY6, CMKBRL2, CC-CKR-8
应用:
WB,IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P51685
规格:
目录价
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Description |
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This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. |
Specification |
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Aliases | CY6, TER1, CCR-8, CKRL1, CDw198, CMKBR8, GPRCY6, CMKBRL2, CC-CKR-8 |
Swissprot | P51685 |
WB Predicted band size | 41 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthetic peptide of human CCR8 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/500-1/2000 |
IHC | 1/50-1/200 |
ELISA | 1/2000-1/5000 |
Product Image
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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Huamn lymphoma tissue, Primary antibody: P03804(CCR8 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
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The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P03804(CCR8 Antibody) at dilution 1/20. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P03804(CCR8 Antibody) at dilution 1/20. (Original magnification: ×200)