Rabbit Polyclonal Antibody to SMARCA4
货号:
P03793
别名:
BRG1, SNF2, SWI2, MRD16, RTPS2, BAF190, SNF2L4, SNF2LB, hSNF2b, BAF190A
应用:
WB,IHC
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
P51532
规格:
目录价
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Description |
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The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. |
Specification |
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Aliases | BRG1, SNF2, SWI2, MRD16, RTPS2, BAF190, SNF2L4, SNF2LB, hSNF2b, BAF190A |
Swissprot | P51532 |
WB Predicted band size | 185 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Synthetic peptide of human SMARCA4 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/200-1/1000 |
IHC | 1/50-1/200 |
ELISA | 1/1000-1/5000 |
Product Image
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Gel: 8%SDS-PAGE, Lysate: 50 μg, Lane 1-3: K562 cells, 293T cells, hepG2 cells, Primary antibody: P03793(SMARCA4 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P03793(SMARCA4 Antibody) at dilution 1/50. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P03793(SMARCA4 Antibody) at dilution 1/50. (Original magnification: ×200)