Rabbit Polyclonal Antibody to KCNH2
货号:
P04017
别名:
ERG1, HERG, LQT2, SQT1, HERG1, Kv11.1
应用:
WB
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
Q12809
规格:
目录价
在线咨询
Description |
---|
This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified. Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1. |
Specification |
|
---|---|
Aliases | ERG1, HERG, LQT2, SQT1, HERG1, Kv11.1 |
Swissprot | Q12809 |
WB Predicted band size | 90 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Synthetic peptide of human KCNH2 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
---|---|
WB | 1/500-1/2000 |
ELISA | 1/1000-1/5000 |