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Rabbit Polyclonal Antibody to KCNH2
货号: P04017
别名: ERG1, HERG, LQT2, SQT1, HERG1, Kv11.1
应用: WB
反应种属: Human, Mouse, Rat
抗体类型: Primary antibody
Swissprot: Q12809
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Description

This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified. Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1.

Specification

Aliases ERG1, HERG, LQT2, SQT1, HERG1, Kv11.1
Swissprot Q12809
WB Predicted band size 90 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen Synthetic peptide of human KCNH2
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

WB 1/500-1/2000
ELISA 1/1000-1/5000
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