Mouse Monoclonal Antibody to RTN3
货号：
20357
别名：
HAP; ASYIP; NSPL2; NSPLII; RTN3-A1
应用：
IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
O95197
规格：
目录价
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Description |
|---|
RTN3, reticulon 3. The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms. |
References |
|---|
| 1. Biochem Biophys Res Commun. 2005 Sep 9;334(4):1198-205. 2. Brain Res Mol Brain Res. 2005 Aug 18;138(2):236-43. 3. FASEB J. 2003 Jul;17(10):1238-47. |
Specification |
|
|---|---|
| Aliases | HAP; ASYIP; NSPL2; NSPLII; RTN3-A1 |
| Entrez GeneID | 10313 |
| Swissprot | O95197 |
| clone | 10A8 |
| WB Predicted band size | 113kDa |
| Host/Isotype | Mouse IgG2a |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of RTN3 expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| IHC | 1/200 - 1/1000 |
| ELISA | 1/10000 |
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