Rabbit Polyclonal Antibody to PFN2
货号:
P04179
别名:
PFL, D3S1319E
应用:
WB,IHC
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
P35080
规格:
目录价
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Description |
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The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. |
Specification |
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Aliases | PFL, D3S1319E |
Swissprot | P35080 |
WB Predicted band size | 15 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Synthetic peptide of human PFN2 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/500-1/2000 |
IHC | 1/25-1/100 |
ELISA | 1/1000-1/5000 |
Product Image
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Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal brain tissue, Primary antibody: P04179(PFN2 Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes
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The image is immunohistochemistry of paraffin-embedded Human brain tissue using P04179(PFN2 Antibody) at dilution 1/30. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P04179(PFN2 Antibody) at dilution 1/30. (Original magnification: ×200)