Rabbit Polyclonal Antibody to LRPAP1
货号:
P04083
别名:
RAP, MRAP, A2RAP, HBP44, A2MRAP
应用:
WB,IHC
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
P30533
规格:
目录价
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Description |
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Low density lipoprotein receptor-related protein associated protein 1 also known as LRPAP1 or RAP is a chaperone protein which in humans is encoded by the LRPAP1 gene. LRPAP1 is involved with trafficking of certain members of the LDL receptor family including LRP1 and LRP2. It is a glycoprotein that binds to the alpha-2-macroglobulin receptor, as well as to other members of the low density lipoprotein receptor family. It acts to inhibit the binding of all know ligands for these receptors, and may prevent receptor aggregation and degradation in the endoplasmic reticulum, thereby acting as a molecular chaperone. It may be under the regulatory control of calmodulin, since it is able to bind calmodulin and be phosphorylated by calmodulin-dependent kinase II. |
Specification |
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Aliases | RAP, MRAP, A2RAP, HBP44, A2MRAP |
Swissprot | P30533 |
WB Predicted band size | 41 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Synthetic peptide of human LRPAP1 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/500-1/2000 |
IHC | 1/50-1/200 |
ELISA | 1/1000-1/5000 |
Product Image
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Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: 293T cells, Human fetal kidney tissue, Primary antibody: P04083(LRPAP1 Antibody) at dilution 1/1600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
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The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P04083(LRPAP1 Antibody) at dilution 1/100. (Original magnification: ×200)