Rabbit Polyclonal Antibody to SMAD7
货号：
P04203
别名：
CRCS3; MADH7; MADH8
应用：
WB,IHC
反应种属：
Human, Mouse, Rat
抗体类型：
Primary antibody
Swissprot：
O15105
规格：
目录价
在线咨询
Description |
|---|
The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. |
Specification |
|
|---|---|
| Aliases | CRCS3; MADH7; MADH8 |
| Swissprot | O15105 |
| WB Predicted band size | 46 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Synthetic peptide of human SMAD7 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/2000 |
| IHC | 1/50-1/200 |
| ELISA | 1/5000-1/10000 |
Product Image
-
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: LO2 cell lysate, Primary antibody: P04203(SMAD7 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 1 minute
-
The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P04203(SMAD7 Antibody) at dilution 1/50. (Original magnification: ×200)
鄂公网安备42018502007531号
