Rabbit Polyclonal Antibody to TNIP3
货号:
P04250
别名:
LIND; ABIN-3
应用:
WB
反应种属:
Human, Mouse
抗体类型:
Primary antibody
Swissprot:
Q96KP6
规格:
目录价
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Description |
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TNIP3, which called LIND, that was upregulated in monocytes infected with Listeria monocytogenes. The predicted 325-amino acid protein contains 3 coiled-coil domains and is most likely localized to the nucleus. Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding. |
Specification |
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Aliases | LIND; ABIN-3 |
Swissprot | Q96KP6 |
WB Predicted band size | 39 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | Synthetic peptide of human TNIP3 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/200-1/1000 |
ELISA | 1/1000-1/2000 |