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Rabbit Polyclonal Antibody to LIN28A
货号: P04297
别名: CSDD1; LIN28; LIN-28; ZCCHC1; lin-28A
应用: IHC
反应种属: Human, Mouse
抗体类型: Primary antibody
Swissprot: Q9H9Z2
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Description

This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues.

Specification

Aliases CSDD1; LIN28; LIN-28; ZCCHC1; lin-28A
Swissprot Q9H9Z2
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Synthetic peptide of human LIN28A
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

IHC 1/25-1/100
ELISA 1/1000-1/2000
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