Rabbit Polyclonal Antibody to NFKB2
货号:
P04378
别名:
p52; p100; H2TF1; LYT10; CVID10; LYT-10; NF-kB2; p49/p100
应用:
WB,IHC
反应种属:
Human, Mouse
抗体类型:
Primary antibody
Swissprot:
Q00653
规格:
目录价
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Description |
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This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. |
Specification |
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Aliases | p52; p100; H2TF1; LYT10; CVID10; LYT-10; NF-kB2; p49/p100 |
Swissprot | Q00653 |
WB Predicted band size | 97 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | Synthetic peptide of human NFKB2 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/500-1/2000 |
IHC | 1/50-1/200 |
ELISA | 1/5000-1/10000 |
Product Image
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Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-3: U251, MCF-7, HT-29 cell lysates, Primary antibody: P04378(NFKB2 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 1 second
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The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P04378(NFKB2 Antibody) at dilution 1/50. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P04378(NFKB2 Antibody) at dilution 1/50. (Original magnification: ×200)