Rabbit Polyclonal Antibody to MCAM
货号:
P04364
别名:
CD146; MUC18; HEMCAM; METCAM; MelCAM
应用:
WB,IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P43121
规格:
目录价
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Description |
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Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration. |
Specification |
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Aliases | CD146; MUC18; HEMCAM; METCAM; MelCAM |
Swissprot | P43121 |
WB Predicted band size | 72 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthetic peptide of human MCAM |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/500-1/2000 |
IHC | 1/40-1/200 |
ELISA | 1/5000-1/10000 |
Product Image
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Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Human leiomyosarcoma tissue lysate, Primary antibody: P04364(MCAM Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 5 seconds
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The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P04364(MCAM Antibody) at dilution 1/40. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P04364(MCAM Antibody) at dilution 1/40. (Original magnification: ×200)