Rabbit Polyclonal Antibody to AKAP12
货号:
P04469
别名:
SSeCKS; AKAP250
应用:
IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q02952
规格:
目录价
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Description |
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The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. |
Specification |
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Aliases | SSeCKS; AKAP250 |
Swissprot | Q02952 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthetic peptide of human AKAP12 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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IHC | 1/50-1/200 |
ELISA | 1/3000-1/10000 |
Product Image
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The image is immunohistochemistry of paraffin-embedded Human brain tissue using P04469(AKAP12 Antibody) at dilution 1/40. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P04469(AKAP12 Antibody) at dilution 1/40. (Original magnification: ×200)