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Rabbit Polyclonal Antibody to Ly6a
货号: P04507
别名: TAP; Sca1; Sca-1; Ly-6A.2; Ly-6A/E; Ly-6E.1
应用: IHC
反应种属: Human, Mouse
抗体类型: Primary antibody
Swissprot: P05533
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Description

The activity of natural killer (NK) cells is regulated by members of multiple receptor families that recognize class I MHC molecules, such as the killer cell inhibitory receptor/leukocyte immunoglobulin-like receptor (KIR/LIR) family and the C-type lectin superfamily. The Ly-6 alloantigens represent a family of phosphatidylinositol anchored proteins that play a role in the process of T lymphocyte activation. Ly-6 expression is commonly induced on T and B lymphocytes after activation by mitogens. Ly-6A/E is a phosphatidylinositol-linked transmembrane member of the Ly-6 family that is produced in humans after 4 weeks of age. ©-interferon and TNF regulate Ly-6A/E at the level of transcription and mRNA stabilization in certain thymocytes and T-cells.

Specification

Aliases TAP; Sca1; Sca-1; Ly-6A.2; Ly-6A/E; Ly-6E.1
Swissprot P05533
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Synthetic peptide of mouse Ly6a
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

IHC 1/20-1/100
ELISA 1/5000-1/10000
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