产品中心
PRODUCT CENTER
首页 »产品中心 »抗体 »科研抗体 »
Rabbit Polyclonal Antibody to ACVR1
货号: P04532
别名: FOP; ALK2; SKR1; TSRI; ACTRI; ACVR1A; ACVRLK2
应用: WB
反应种属: Human, Mouse, Rat
抗体类型: Primary antibody
Swissprot: Q04771
规格:
目录价
在线咨询

Description

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.

Specification

Aliases FOP; ALK2; SKR1; TSRI; ACTRI; ACVR1A; ACVRLK2
Swissprot Q04771
WB Predicted band size 57 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen Synthetic peptide of human ACVR1
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

WB 1/200-1/1000
ELISA 1/2000-1/5000
联系我们
  • 电话:17771420241 18911818852
  • 联系人:刘经理
  • 地址:湖北省武汉市东湖新技术开发区高新大道666号光谷生物城C6栋C6403、C6404
微信公众号
版权所有 © 武汉博开生物科技有限公司  备案编号:鄂ICP备2024052832号-1鄂公网安备42018502007531号
17771420241 18911818852