Rabbit Polyclonal Antibody to RBL2
货号：
P04620
别名：
Rb2; P130
应用：
WB,IHC
反应种属：
Human, Mouse, Rat
抗体类型：
Primary antibody
Swissprot：
Q08999
规格：
目录价
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Description |
|---|
Retinoblastoma-like protein 2 is a protein that in humans is encoded by the RBL2 gene. Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. |
Specification |
|
|---|---|
| Aliases | Rb2; P130 |
| Swissprot | Q08999 |
| WB Predicted band size | 128 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Synthetic peptide of human RBL2 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/200-1/1000 |
| IHC | 1/30-1/150 |
| ELISA | 1/5000-1/10000 |
Product Image
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Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Lncap cell, Primary antibody: P04620(RBL2 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 4 minutes
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The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P04620(RBL2 Antibody) at dilution 1/40. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human brain tissue using P04620(RBL2 Antibody) at dilution 1/40. (Original magnification: ×200)
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