Rabbit Polyclonal Antibody to CAV1
货号:
P04673
别名:
CGL3; PPH3; BSCL3; VIP21; MSTP085
应用:
WB,IHC
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
Q03135
规格:
目录价
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Description |
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The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1. |
Specification |
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Aliases | CGL3; PPH3; BSCL3; VIP21; MSTP085 |
Swissprot | Q03135 |
WB Predicted band size | 20 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Synthetic peptide of human CAV1 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/1000-1/5000 |
IHC | 1/50-1/200 |
ELISA | 1/2000-1/10000 |
Product Image
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Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-6: Human fetal muscle tissue, Human fetal lung tissue, Human leiomyosarcoma tissue, mouse lung, Mouse heart tissue, NIH/3T3 cells, Primary antibody: P04673(CAV1 Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P04673(CAV1 Antibody) at dilution 1/40. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P04673(CAV1 Antibody) at dilution 1/40. (Original magnification: ×200)