Rabbit Polyclonal Antibody to CCDC88A
货号:
P04685
别名:
APE; GIV; GRDN; HkRP1; GIRDIN; KIAA1212
应用:
IHC
反应种属:
Human, Mouse
抗体类型:
Primary antibody
Swissprot:
Q3V6T2
规格:
目录价
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Description |
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This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Specification |
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Aliases | APE; GIV; GRDN; HkRP1; GIRDIN; KIAA1212 |
Swissprot | Q3V6T2 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | Synthetic peptide of human CCDC88A |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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IHC | 1/50-1/200 |
ELISA | 1/1000-1/5000 |
Product Image
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The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P04685(CCDC88A Antibody) at dilution 1/50. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P04685(CCDC88A Antibody) at dilution 1/50. (Original magnification: ×200)