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Rabbit Polyclonal Antibody to CCDC88A
货号: P04685
别名: APE; GIV; GRDN; HkRP1; GIRDIN; KIAA1212
应用: IHC
反应种属: Human, Mouse
抗体类型: Primary antibody
Swissprot: Q3V6T2
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Description

This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Specification

Aliases APE; GIV; GRDN; HkRP1; GIRDIN; KIAA1212
Swissprot Q3V6T2
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Synthetic peptide of human CCDC88A
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

IHC 1/50-1/200
ELISA 1/1000-1/5000
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