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Rabbit Polyclonal Antibody to EID3
货号: P04841
别名: NS4EB; NSE4B; NSMCE4B
应用: WB,IHC
反应种属: Human, Mouse
抗体类型: Primary antibody
Swissprot: Q8N140
规格:
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Description

EID3 is highly expressed in testis and shows homology to a region of EID1 implicated in binding to CBP/p300. EID3 acts as a potent inhibitor of nuclear receptor transcriptional activity by a mechanism that is independent of direct interactions with nuclear receptors, including SHP. Furthermore, EID3 directly binds to and blocks the SRC-1 interacting domain of CBP, which has been implicated to act as the interaction surface for nuclear receptor co-activators. Consistent with this idea, EID3 prevents recruitment of CBP to a natural nuclear receptor-regulated promoter.

Specification

Aliases NS4EB; NSE4B; NSMCE4B
Swissprot Q8N140
WB Predicted band size 38 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Synthetic peptide of human EID3
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

WB 1/200-1/1000
IHC 1/25-1/100
ELISA 1/1000-1/2000
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