Mouse Monoclonal Antibody to HDAC4
货号：
20423
别名：
HD4; HDACA; HA6116; HDAC-A; KIAA0288; HDAC4
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P56524
规格：
目录价
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Description |
|---|
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. |
References |
|---|
| 1. Biochem Biophys Res Commun. 2008 Dec 19;377(3):852-6. 2. Curr Top Med Chem. 2009;9(3):235-40. 3. Nucleic Acids Res. 2010 May;38(9):2813-24. |
Specification |
|
|---|---|
| Aliases | HD4; HDACA; HA6116; HDAC-A; KIAA0288; HDAC4 |
| Entrez GeneID | 9759 |
| Swissprot | P56524 |
| clone | 7B2 |
| WB Predicted band size | 119kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human HDAC4 expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| ELISA | 1/10000 |
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