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Mouse Monoclonal Antibody to DKK3
货号: 30010
别名: RIG; REIC
应用: WB,FCM
反应种属: Human,Monkey
抗体类型: Primary antibody
Swissprot: Q9UBP4
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Description

Dkk-3 (Dickkopf-3) is a member of the dickkopf family. It is a 350 amino acid secreted glycoprotein that is composed of an N-terminal signal peptide and two conserved cysteine-rich domains, which are separated by a 12 amino acid linker region. This secreted protein is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene.

References

1. Virchows Arch. 2009 Jun;454(6):639-46.
2. Gene. 2002 Jan 9;282(1-2):151-8.
3. J Urol. 2004 Mar;171(3):1314-8.

Specification

Aliases RIG; REIC
Entrez GeneID 27122
Swissprot Q9UBP4
clone 4G7
WB Predicted band size 38kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Monkey
Immunogen Purified recombinant fragment of human DKK3 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.

Application

WB 1/500 - 1/2000
FCM 1/200 - 1/400
ELISA 1/10000
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