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Mouse Monoclonal Antibody to CDC25C
货号: 30022
别名: CDC25; CDC25C
应用: WB,IHC
反应种属: Human
抗体类型: Primary antibody
Swissprot: P30307
规格:
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Description

Cdc25C is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It has been highly conserved during evolution and it plays a key role in the regulation of cell division. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Cdc25C is mainly expressed in G2 phase. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.

References

1. Cancer Cell. 2007 Mar;11(3):275-89.
2. Int J Biochem Cell Biol. 2007;39(9):1707-13.
3. Int J Cancer. 2010 May 1;126(9):2199-210.

Specification

Aliases CDC25; CDC25C
Entrez GeneID 995
Swissprot P30307
clone 1F12
WB Predicted band size 58kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CDC25C expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500 - 1/2000
IHC 1/200 - 1/1000
ELISA 1/10000
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