Mouse Monoclonal Antibody to CDC25C
货号:
30022
别名:
CDC25; CDC25C
应用:
WB,IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P30307
规格:
目录价
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Description |
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Cdc25C is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It has been highly conserved during evolution and it plays a key role in the regulation of cell division. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Cdc25C is mainly expressed in G2 phase. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. |
References |
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1. Cancer Cell. 2007 Mar;11(3):275-89. 2. Int J Biochem Cell Biol. 2007;39(9):1707-13. 3. Int J Cancer. 2010 May 1;126(9):2199-210. |
Specification |
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Aliases | CDC25; CDC25C |
Entrez GeneID | 995 |
Swissprot | P30307 |
clone | 1F12 |
WB Predicted band size | 58kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human CDC25C expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500 - 1/2000 |
IHC | 1/200 - 1/1000 |
ELISA | 1/10000 |