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Rabbit Polyclonal Antibody to MECOM
货号: P06470
别名: EVI1; MDS1; KMT8E; PRDM3; RUSAT2; MDS1-EVI1; AML1-EVI-1
应用: WB,IHC
反应种属: Human, Mouse
抗体类型: Primary antibody
Swissprot: Q03112
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Description

The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.

Specification

Aliases EVI1; MDS1; KMT8E; PRDM3; RUSAT2; MDS1-EVI1; AML1-EVI-1
Swissprot Q03112
WB Predicted band size 118 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Synthetic peptide of human MECOM
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

WB 1/200-1/1000
IHC 1/30-1/150
ELISA 1/5000-1/10000
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