Mouse Monoclonal Antibody to PARP
货号：
30016
别名：
PARP; PPOL; ADPRT; ADPRT1; PARP-1; pADPRT-1; PARP1
应用：
WB,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P09874
规格：
目录价
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Description |
|---|
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. |
References |
|---|
| 1. Cytogenet Cell Genet. 1992;61(3):172-4. 2. J Immunol. 1997 Dec 1;159(11):5246-52. 3. J Biol Chem. 2001 Dec 7;276(49):45588-97. |
Specification |
|
|---|---|
| Aliases | PARP; PPOL; ADPRT; ADPRT1; PARP-1; pADPRT-1; PARP1 |
| Entrez GeneID | 142 |
| Swissprot | P09874 |
| clone | 7A10 |
| WB Predicted band size | 117kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide of human PARP, conjugated to KLH. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
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