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Mouse Monoclonal Antibody to TCF3
货号: 30012
别名: E2A; ITF1; VDIR; bHLHb21; MGC129647; MGC129648; TCF3
应用: WB,FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: P15923
规格:
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Description

Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer.

References

1.J Biol Chem. 2000 Oct 27;275(43):33567-73.
2.Mol Cell Biol. 2001 Mar;21(5):1866-73.
3.J Biol Chem. 2003 Jan 24;278(4):2370-6. Epub 2002 Nov 14.

Specification

Aliases E2A; ITF1; VDIR; bHLHb21; MGC129647; MGC129648; TCF3
Entrez GeneID 6929
Swissprot P15923
clone 6B8
WB Predicted band size 67.6kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human TCF3 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.

Application

WB 1/500 - 1/2000
FCM 1/200 - 1/400
ELISA 1/10000
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