Mouse Monoclonal Antibody to ETV5
货号:
30055
别名:
ERM; ETV5
应用:
WB
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P41161
规格:
目录价
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Description |
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ETS variant 5,transcription factor of the ETS family,divergent member of the winged helix-turn-helix superfamily,expressed in brain,placenta and other tissues involved in development. Tissue specificity: Ubiquitous. ERM is expressed in Sertoli cells and spermatogonial stem cells (SSCs). Studies on knockout mice have shown that it is required for SSC self-renewal but not differentiation, thus affected mice exhibit progressive germ cell depletion. |
References |
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1. Immunity. 2002 Oct;17(4):401-12. 2. Clin Cancer Res. 2004 Nov 1;10(21):7297-303. 3. J Hum Genet. 2009 Dec;54(12):727-31. |
Specification |
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Aliases | ERM; ETV5 |
Entrez GeneID | 2119 |
Swissprot | P41161 |
clone | 3H3 |
WB Predicted band size | 58kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human ETV5 expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500 - 1/2000 |
ELISA | 1/10000 |