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Mouse Monoclonal Antibody to ETV5
货号: 30055
别名: ERM; ETV5
应用: WB
反应种属: Human
抗体类型: Primary antibody
Swissprot: P41161
规格:
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Description

ETS variant 5,transcription factor of the ETS family,divergent member of the winged helix-turn-helix superfamily,expressed in brain,placenta and other tissues involved in development. Tissue specificity: Ubiquitous. ERM is expressed in Sertoli cells and spermatogonial stem cells (SSCs). Studies on knockout mice have shown that it is required for SSC self-renewal but not differentiation, thus affected mice exhibit progressive germ cell depletion.

References

1. Immunity. 2002 Oct;17(4):401-12.
2. Clin Cancer Res. 2004 Nov 1;10(21):7297-303.
3. J Hum Genet. 2009 Dec;54(12):727-31.

Specification

Aliases ERM; ETV5
Entrez GeneID 2119
Swissprot P41161
clone 3H3
WB Predicted band size 58kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human ETV5 expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500 - 1/2000
ELISA 1/10000
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