Rabbit Polyclonal Antibody to APIP
货号：
P07034
别名：
APIP2, CGI29, CGI-29, MMRP19, dJ179L10.2
应用：
WB,IHC
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
Q96GX9
规格：
目录价
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Description |
|---|
APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury.The protein highly expressed in skeletal muscle and heart and binds to the CARD of Apaf-1 in competition with caspase-9. Exogenous APIP inhibits cytochrome c-induced activation of caspase-3 and caspase-9, and suppresses cell death triggered by mitochondrial apoptotic stimuli through inhibiting the downstream activity of cytochrome c released from mitochondria. |
Specification |
|
|---|---|
| Aliases | APIP2, CGI29, CGI-29, MMRP19, dJ179L10.2 |
| Swissprot | Q96GX9 |
| WB Predicted band size | 27 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human APIP |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/200-1/1000 |
| IHC | 1/25-1/100 |
| ELISA | 1/500-1/5000 |
Product Image
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Gel: 10%SDS-PAGE, Lysate: 60 μg, Lane: Mouse heart tissue, Primary antibody: P07034(APIP Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P07034(APIP Antibody) at dilution 1/25. (Original magnification: ×200)
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