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Mouse Monoclonal Antibody to ALPP
货号: 30061
别名: ALP; PALP; PLAP; FLJ61142; ALPP
应用: WB,IHC
反应种属: Human
抗体类型: Primary antibody
Swissprot: P05187
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Description

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.

References

1. J Cell Biochem. 2003 Apr 1;88(5):1025-37.
2. J Mol Biol. 2005 Jul 15;350(3):441-51.

Specification

Aliases ALP; PALP; PLAP; FLJ61142; ALPP
Entrez GeneID 250
Swissprot P05187
clone 3E5
WB Predicted band size 58kDa
Host/Isotype Mouse IgG2b
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human ALPP expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500 - 1/2000
IHC 1/200 - 1/1000
ELISA 1/10000
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