Rabbit Polyclonal Antibody to APEX1
货号:
P07075
别名:
APE; APX; APE1; APEN; APEX; HAP1; REF1
应用:
WB,IHC
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
P27695
规格:
目录价
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Description |
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Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. |
Specification |
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Aliases | APE; APX; APE1; APEN; APEX; HAP1; REF1 |
Swissprot | P27695 |
WB Predicted band size | 36 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Fusion protein of human APEX1 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/500-1/2000 |
IHC | 1/15-1/50 |
ELISA | 1/2000-1/5000 |
Product Image
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Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-6: Hela cells, human liver cancer tissue, Raji cells, Jurkat cells, 293T cells, PC3 cells, Primary antibody: P07075(APEX1 Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P07075(APEX1 Antibody) at dilution 1/20. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P07075(APEX1 Antibody) at dilution 1/20. (Original magnification: ×200)