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Mouse Monoclonal Antibody to KLHL12
货号: 30058
别名: DKIR; C3IP1; FLJ27152; KLHL12
应用: WB
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q53G59
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Description

Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.Tissue specificity: Highly expressed in testis and at lower levels in the submandibular salivary gland.

References

1. Exp Cell Res. 2004 Oct 15;300(1):72-83.
2. Gene. 1994 Jan 28;138(1-2):171-4.

Specification

Aliases DKIR; C3IP1; FLJ27152; KLHL12
Entrez GeneID 59349
Swissprot Q53G59
clone 2G2
WB Predicted band size 63kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human KLHL12 expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500 - 1/2000
ELISA 1/10000
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