Mouse Monoclonal Antibody to PTH1R
货号：
30085
别名：
PFE; PTHR; PTHR1; MGC138426; MGC138452; PTH1R
应用：
IHC,IF
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
Q03431
规格：
目录价
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Description |
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The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. |
References |
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| 1. Int J Cancer. 2007 Sep 1;121(5):943-54. 2. Mol Endocrinol. 2008 Jan;22(1):156-66. |
Specification |
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|---|---|
| Aliases | PFE; PTHR; PTHR1; MGC138426; MGC138452; PTH1R |
| Entrez GeneID | 5745 |
| Swissprot | Q03431 |
| clone | 4D2 |
| WB Predicted band size | 66kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Purified recombinant fragment of human PTH1R expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| IHC | 1/200 - 1/1000 |
| IF | 1/200 - 1/1000 |
| ELISA | 1/10000 |
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