Rabbit Polyclonal Antibody to ARC
货号:
P07119
别名:
Arg3.1
应用:
WB,IHC
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
Q7LC44
规格:
目录价
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Description |
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Arc (for activity-regulated cytoskeleton-associated protein) is a growth factor and immediate early gene that is enriched in brain. Arc mRNA and protein levels are induced by neuronal activity, which is necessary to stimulate neuroplasticity, indicating a potential role for Arc in activity-dependent changes in dendrite function. Arc expression has been detected in neuronal cell bodies and dendrites in the hippocampus, amygdala, hypothalamus, striatum and cortex. Arc has been shown to localize to the cytoskeleton of neuronal cells and appears to colocalize with F-Actin, although it may associate with an Actin-associated protein rather than directly with F-Actin. It has been shown that cocaine-stimulated neuronal activity results in increased Arc mRNA levels in striatum. |
Specification |
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Aliases | Arg3.1 |
Swissprot | Q7LC44 |
WB Predicted band size | 45 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Fusion protein of human ARC |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/200-1/1000 |
IHC | 1/50-1/200 |
ELISA | 1/2000-1/5000 |
Product Image
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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human lymphoma tissue, Primary antibody: P07119(ARC Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P07119(ARC Antibody) at dilution 1/25. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P07119(ARC Antibody) at dilution 1/25. (Original magnification: ×200)