Mouse Monoclonal Antibody to STAT6
货号：
30068
别名：
STAT6B; STAT6C; D12S1644; IL-4-STAT; STAT6
应用：
WB,IF
反应种属：
Human,Mouse,Rat,Monkey
抗体类型：
Primary antibody
Swissprot：
P42226
规格：
目录价
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Description |
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STAT6 protein is a transcription factor activated by cytokines, particularly interleukin 4 and IL 13. (STAT6-/-) were found to be deficient in IL 4 mediated functions including Th2 helper T cell differentiation, expression of cell surface markers, T cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL 4 mediated proliferation. STAT6 mRNA has been detected in peripheral bloodlymphocytes, colon, intestine, ovary, prostate,thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response. |
References |
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| 1. Pediatr Nephrol. 2009 Mar;24(3):489-95. 2. Mol Immunol. 2009 Jun;46(10):2080-9. 3. Am J Hum Genet. 2009 Nov;85(5):628-42. |
Specification |
|
|---|---|
| Aliases | STAT6B; STAT6C; D12S1644; IL-4-STAT; STAT6 |
| Entrez GeneID | 6778 |
| Swissprot | P42226 |
| clone | 7D3 |
| WB Predicted band size | 94kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat,Monkey |
| Immunogen | Purified recombinant fragment of human STAT6 expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| IF | 1/200 - 1/1000 |
| ELISA | 1/10000 |
Product Image
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Western blot analysis using STAT6 mouse mAb against HEK293 (1), NIH/3T3 (2), MCF-7 (3), Raw246.7 (4) and PC-12 (5) cell lysate.
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Immunofluorescence analysis of Hela cells using STAT6 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin
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