Rabbit Polyclonal Antibody to CUL7
货号:
P07228
别名:
3M1; KIAA0076; dJ20C7.5
应用:
WB,IHC
反应种属:
Human, Rat
抗体类型:
Primary antibody
Swissprot:
Q14999
规格:
目录价
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Description |
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The protein encoded by this gene is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in this gene are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for this gene. CUL-7 is highly expressed in fetal kidney and adult skeletal muscle in addition to abundant expression in fetal brain, and adult pancreas, kidney, placenta and heart. It is also detected in trophoblasts, lymphoblasts, osteoblasts, chondrocytes and skin fibroblasts. |
Specification |
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Aliases | 3M1; KIAA0076; dJ20C7.5 |
Swissprot | Q14999 |
WB Predicted band size | 191 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Rat |
Immunogen | Fusion protein of human CUL7 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/200-1/1000 |
IHC | 1/25-1/100 |
ELISA | 1/5000-1/10000 |
Product Image
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Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: A431 cell, Primary antibody: P07228(CUL7 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 seconds
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The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P07228(CUL7 Antibody) at dilution 1/35. (Original magnification: ×200)