Mouse Monoclonal Antibody to NFKBIB
货号：
30082
别名：
IKBB; TRIP9; NFKBIB
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q15653
规格：
目录价
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Description |
|---|
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.Tissue specificity: Expressed in all tissues examined. |
References |
|---|
| 1. Mol Cell Biol. 2004 Apr;24(7):3048-56. 2. J Biol Chem. 2004 Oct 15;279(42):44030-8. 3. J Bone Miner Res. 2009 Dec;24(12):2039-49. |
Specification |
|
|---|---|
| Aliases | IKBB; TRIP9; NFKBIB |
| Entrez GeneID | 4793 |
| Swissprot | Q15653 |
| clone | 7B4 |
| WB Predicted band size | 45kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human NFKBIB expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| ELISA | 1/10000 |
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