Mouse Monoclonal Antibody to VCAM1
货号:
30045
别名:
CD106; MGC99561; INCAM-100; DKFZp779G2333; VCAM1
应用:
WB,IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P19320
规格:
目录价
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Description |
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This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.Tissue specificity: Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue.INVITROGEN: CD106 is expressed on bone marrow stromal cells, myeloid cells, and endothelial cells. |
References |
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1. Cell Adh Migr. 2009 Oct;3(4):369-72. 2. Arthritis Rheum. 2010 Jan;62(1):105-16. |
Specification |
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Aliases | CD106; MGC99561; INCAM-100; DKFZp779G2333; VCAM1 |
Entrez GeneID | 7412 |
Swissprot | P19320 |
clone | 6G9 |
WB Predicted band size | 81kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human VCAM1 expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500 - 1/2000 |
IHC | 1/200 - 1/1000 |
ELISA | 1/10000 |
Product Image
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Western blot analysis using VCAM1 mouse mAb against HUVEC (1) and EC (2) cell lysate.
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Immunohistochemical analysis of paraffin-embedded human lung cancer (A) and colon cancer (B) using VCAM1 mouse mAb with DAB staining.
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Immunohistochemical analysis of paraffin-embedded human Placenta tissues using VCAM1 mouse mAb