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Mouse Monoclonal Antibody to VCAM1
货号: 30045
别名: CD106; MGC99561; INCAM-100; DKFZp779G2333; VCAM1
应用: WB,IHC
反应种属: Human
抗体类型: Primary antibody
Swissprot: P19320
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Description

This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.Tissue specificity: Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue.INVITROGEN: CD106 is expressed on bone marrow stromal cells, myeloid cells, and endothelial cells.

References

1. Cell Adh Migr. 2009 Oct;3(4):369-72.
2. Arthritis Rheum. 2010 Jan;62(1):105-16.

Specification

Aliases CD106; MGC99561; INCAM-100; DKFZp779G2333; VCAM1
Entrez GeneID 7412
Swissprot P19320
clone 6G9
WB Predicted band size 81kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human VCAM1 expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500 - 1/2000
IHC 1/200 - 1/1000
ELISA 1/10000
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