Mouse Monoclonal Antibody to KDM4A
货号：
30087
别名：
JMJD2; JHDM3A; JMJD2A; KIAA0677; KDM4A
应用：
IHC,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
O75164
规格：
目录价
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Description |
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This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. |
References |
|---|
| 1. Genome Res. 2004 Sep;14(9):1711-8. 2. Nat Methods. 2005 Aug;2(8):591-8. 3. Cell. 2006 May 19;125(4):691-702. |
Specification |
|
|---|---|
| Aliases | JMJD2; JHDM3A; JMJD2A; KIAA0677; KDM4A |
| Entrez GeneID | 9682 |
| Swissprot | O75164 |
| clone | 5H1 |
| WB Predicted band size | 120kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human KDM4A expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
Application |
|
|---|---|
| IHC | 1/200 - 1/1000 |
| IF | 1/200 - 1/1000 |
| ELISA | 1/10000 |
Product Image
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Immunofluorescence analysis of NTERA-2 cells using KDM4A mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
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Immunohistochemical analysis of paraffin-embedded human colon cancer tissues (left) and human larynx cancer tissues (right) using KDM4A mouse mAb with DAB staining.
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